Testing Status of Avobenzone 10055

 

CASRN: 70356-09-1

Formula: C20-H22-O3

Synonyms/Common Names

  • Butyl methoxydibenzoylmethane
  • 1,3-Propanedione, 1-(4-(1,1-dimethylethyl)phenyl)-3-(4- methoxyphenyl)-

Known Uses

Ingredient used in sunscreen products

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • 3 days Hershberger Assay (Gavage)  (K10380B)  Completed 
    • Citation: FINAL Report: The Hershberger Bioassay for Ensulizole and Avobenzone 07 November 2012
    • Female Rats: Harlan Sprague-Dawley
    • Dose: 0, 320, 1000.
  • 3 days Uterotrophic Assay (Gavage)  (K10380)  Completed 
    • Citation: FINAL Report: The Uterotrophic Assay with Avobenzone, Ensulizole, Homosalate, and Padimate-O 07 November 2012
    • Female Rats: Harlan Sprague-Dawley
    • Dose: 0, 320, 1000.

in vitro Testing

  • Androgen Receptor Binding Assay  (V10380)  Completed 
    • Androgen Receptor Binding [ARB] (Rat Prostate Cytosol)
  • Estrogen Receptor Binding Assay (Gavage)  (V10380)  Completed 
    • Estrogen Receptor Binding [ERB] (Rat Uterine Cytosol)
    • Rats: Harlan Sprague-Dawley