National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-10060-g

Testing Status of Bromobenzene - 10060-G

 

CASRN: 108-86-1

Formula: C6-H5-Br

Synonyms/Common Names

  • Phenyl bromide

Known Uses

Chemical intermediate. Solvent. Organic synthesis. Motor oil additive.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 4 days (Inhalation)  (C55492C)  Completed 
    • Rats: F344/N; Mice: B6C3F1
  • 13-Week (Inhalation)  (C55492C)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R&FM: 0, 10, 300, MM: 0, 10, 100 PPM/10 PER GROUP.
  • 13-Week (Gavage)  (C55492D)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: 0, 50, 600 MG/KG/10 PER GROUP.

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (544069)  Completed 
    • Citation: Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176
    • Sister Chromatid Exchange Weakly Positive 
    • Chromosome Aberrations Negative 
  • Salmonella  (818178)  Completed 
    • Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
    •  Negative 
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