National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-10107-s

Testing Status of 4,4'-Diamino-2,2'-stilbenedisulfonic acid - 10107-S

 

CASRN: 81-11-8

Formula: C14-H14-N2-O6-S2

Synonyms/Common Names

  • Amsonic acid
  • Amsonic acid
  • 2,2'-(1,2-Ethylenediyl)bis(5-aminobenzenesulfonic acid)

Known Uses

Chemical intermediate for dyes and fluorescent brighteners.

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Absorption Disposition Metabolism Elimination (Gavage)  (S0201)  Completed 
    • Male and Female Rats: F344/N
  • Toxicokinetic Study (Dosed-Feed; Intravenous)  (S0136)  Completed 
    • Male and Female Rats

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (610829)  Completed 
    • Citation: Loveday, K.S., Anderson, B.E., Resnick, M.A., and Zeiger, E. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro V: Results with 46 chemicals Environ. Molec. Mutagen. Vol. 16 (1990) 272-303
    • Sister Chromatid Exchange Negative 
    • Chromosome Aberrations Negative 
  • In Vitro Cytogenetics (CA/SCE)  (932349)  Completed 
    • Sister Chromatid Exchange Negative 
    • Chromosome Aberrations Negative 
  • Salmonella  (636704)  Completed 
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
    •  Negative 
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