National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-10116-w

Testing Status of Dimethyl sulfoxide - 10116-W

 

CASRN: 67-68-5

Formula: C2-H6-O-S

Synonyms/Common Names

  • Sulfinylbismethane (9CI)

Known Uses

Anti-inflammatory, drug carrier, solvent, in cleaners, in pesticides, for cell preservation, in plant pathology and nutrition. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • C. elegans  (S0860)  Completed 
    • C. elegans
    • Dose: feed (0, .347, .693, 1.33, 2.13, 2.8, 3.47, 4.27, 4.93, 5.6, 6.3, 6.9) 4/13/06 repro (0, .5, 1, 1.5, 2, 2.5, 3, 3.5, 4, 4.5, 5.0, 5.5) 7/09/04 growth (0, .1, .16, .25, .40, .63, 1, 1.6, 2.5, 4.0, 6.3, 10) 5/04/06.

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (272561)  Completed 
    • Citation: Loveday, K.S., Anderson, B.E., Resnick, M.A., and Zeiger, E. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro V: Results with 46 chemicals Environ. Molec. Mutagen. Vol. 16 (1990) 272-303
    • Sister Chromatid Exchange Negative 
    • Chromosome Aberrations Negative 
  • Salmonella  (229896)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
    •  Negative 
  • Salmonella  (939205)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
    •  Negative 
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