Testing Status of Sodium azide 10164-D

 

CASRN: 26628-22-8

Formula: N3-Na

Synonyms/Common Names

  • Hydrazoic acid, sodium salt

Known Uses

Herbicide, pesticide, reagent, diagnostic medicine preservative, fungicide, fumigant (HSDB 1990). It is the principal chemical used to generate nitrogen gas in automobile safety airbags and airplane escape chutes and is a broad-spectrum biocide used in both research and agriculture.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 14-Day (Gavage)  (C06462)  Completed 
    • Rats: F344/N
  • 13-Week (Gavage)  (C06462)  Completed 
    • Rats: F344/N
    • Dose: RATS ONLY:0, .063, 4 MG/ML/10 PER GROUP.

Long-Term Carcinogenicity

  • 2 years (Gavage)  (C06462)  Report Complete 
    • TR-389 (NIH Number: 91-2844)  (Peer Review Approval 04/25/1990A )
      Toxicology and Carcinogeneis Studies of Sodium Azide (CASRN 26628-22-8) in F344 Rats (Gavage Studies)
    • Rats: F344/N
    • Carcinogenesis Results
      • Male Rats No Evidence 
      • Female Rats No Evidence 
    • Dose: RATS ONLY:0, 5, 10 MG/KG/60 PER GROUP.

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (166603)  Completed 
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Negative 
  • Salmonella  (201201)  Completed 
    • Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1984) Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol. Environ. Mutagen. 6 (Suppl. 2): 1-251.
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
    •  Positive 
  • Salmonella  (A90612)  Completed 
    • Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1984) Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol. Environ. Mutagen. 6 (Suppl. 2): 1-251.
    •  Positive 
  • Salmonella  (G10164)  Completed 
    •  Positive 
  • Salmonella  (N-9164)  Completed 
    • Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1984) Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol. Environ. Mutagen. 6 (Suppl. 2): 1-251.
    • Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol Environ. Mutagen. Vol. 6 (Suppl 2) (1984) 1-251