Testing Status of Cadmium oxide 10212-K

 

CASRN: 1306-19-0

Formula: Cd-O

Synonyms/Common Names

  • Cadmium monoxide

Known Uses

Electroplating, intermediate, in alloys, batteries, glass and ceramic glazes, in plastics, veterinary medicine. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 2 weeks (Inhalation)  (C02551B)  Completed 
    • Rats: Sprague Dawley; Mice: Swiss CD-1
    • Dose: RATS & MICE: 0, 0.1, 0.3, 1.0, 3.0 OR 10 MG/M3 (5/S/S).
  • 2 weeks (Inhalation)  (C02551)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R, M: 0, 0.1, 0.3, 1.0, 3.0 OR 10 MG/M3 (5/S/S).
  • 3 weeks (Inhalation)  (C02551B)  Report Complete 
    • TOX-39 (NIH Number: 95-3388)  (Tox Peer Review 07/00/1994A )
      Toxicity Studies of Cadmium Oxide (CASRN 1306-19-0) Administered by Inhalation to F344/N Rats and B6C3F1 Mice
    • Rats: Sprague Dawley; Mice: Swiss CD-1
    • Dose: RATS & MICE: 0, 0.025, 0.05, 0.1, 0.25 OR 1.0 MG/MG (10/S/S).
  • 13 weeks (Inhalation)  (C02551)  Report Complete 
    • TOX-39 (NIH Number: 95-3388)  (Tox Peer Review 07/00/1994A )
      Toxicity Studies of Cadmium Oxide (CASRN 1306-19-0) Administered by Inhalation to F344/N Rats and B6C3F1 Mice
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R, M: 0, 0.025, 0.05, 0.1, 0.25 OR 1.0 MG/M3 (10/S/S).

Special Studies

  • Absorption Disposition Metabolism Elimination (Inhalation)  (S0744)  Completed 
    • Citation: Dill JA, Greenspan BJ, Mellinger KH, Roycroft JH, Dunnick J. Disposition of inhaled cadmium oxide aerosol in the rat. Inhalation Toxicology. 1994;6:379-93.
    • Male Rats: F344/N
    • Dose: 0.0, 0.10, 0.25, or 1.0 mg/m3.

Genetic Toxicology

  • Micronucleus  (A49643)  Completed 
    • Mice: B6C3F1
    • Male Negative 
    • Female Negative 
  • Salmonella  (748073)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Negative