Testing Status of 2,4-Dinitroaniline 10214-T

 

CASRN: 97-02-9

Formula: C6-H5-N3-O4

Synonyms/Common Names

  • 2,4-Dinitrobenzenamine

Known Uses

Chemical intermediate for C.I. Pigment orange 5. Used in preparation of azo dyes (Merck 1989).

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Absorption Disposition Metabolism Elimination (Gavage; Intravenous)  (S0032)  Completed 
    • Citation: Matthews HB, Chopade HM, Smith RW, Burka LT. Disposition of 2,4-dinitroaniline in the male F-344 rat. Xenobiotica. 1986 Jan;16(1):1-10. Pubmed Abstract
    • Male Rats: F344/N
    • Dose: GAV:0.183, 18.3, 164.7 MG/KG; IV:18.3 MG/KG.

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (346627)  Completed 
    • Sister Chromatid Exchange Negative 
    • Chromosome Aberrations Negative 
  • Drosophila  (643155)  Completed 
    • Citation: Woodruff, R.C., Mason, J.M., Valencia, R., and Zimmering, S. Chemical mutagenesis testing in Drosophila: V. Results of 53 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 677-702
    • Reciprocal Translocation/Sex-Linked Recessive Lethal Negative 
  • Mouse Lymphoma  (044132)  Completed 
    • Mice
    •  Negative 
  • Salmonella  (059613)  Completed 
    • Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
    •  Positive