National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-10215-x

Testing Status of Neohesperidin dihydrochalcone - 10215-X

 

CASRN: 20702-77-6

Formula: C28-H36-O15

Synonyms/Common Names

  • 1-(4-((2-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2,6-dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)propan-1-one

Known Uses

Not currently used. Proposed as a sweetening agent in chewing gum, candies, toothpaste, mouthwash, drugs & fruit juice. Obtained from narinogen, which occurs naturally in grapefruit (Merck 1989)

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • Salmonella  (924946)  Completed 
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
    •  Negative 
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