National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-10238-a

Testing Status of Seneciphylline - 10238-A

 

CASRN: 480-81-9

Formula: C18-H23-N-O5

Synonyms/Common Names

  • 13,19-Didehydro-12-hydroxysenecionan-11,16-dione (9CI)

Known Uses

Natural constituent of senecio plant, hepatotoxic pyrrolizidine alkaloid

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • Salmonella  (953448)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
    •  Positive 
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