Testing Status of N-Isopropyl-N'-phenyl-p-phenylenediamine 10263-E


CASRN: 101-72-4

Formula: C15-H18-N2

Synonyms/Common Names

  • N-(1-Methylethyl)-N'-phenyl-1,4-benzenediamine (9CI)
  • P-Isopropylaminodiphenylamine

Known Uses

Protection of rubber against oxidiation, ozone, flex-cracking and poisoning by copper and manganese.

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (042763)  Completed 
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Positive 
  • Salmonella  (011445)  Completed 
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
    •  Negative 

Organ Systems Toxicity

  • 7 to 14 GD Short-Term in vivo Repro. Tox. (Gavage)  (T0051)  Completed 
    • Citation: Screening of Priority Chemicals for Potential Reproductive Hazard
    • Female Mice: Swiss
    • Dose: 800 MG/KG BODY WEIGHT.