National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-10299-c

Testing Status of Polyethylene glycol 200 - 10299-C

 

CASRN: 25322-68-3

Formula: (C2-H4-O)mult-H2-O

Synonyms/Common Names

  • alpha-Hydro-omega-hydroxypoly(oxy-1,2-ethanediyl)(9CI)

Known Uses

Used to stabilize and dissolve drugs, as emollient, in ointment bases, and suppositories. In solvents and softening agents. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • C. elegans  (S0931)  Completed 
    • C. elegans
    • Dose: feed: (0,1.6,2.0,2.5,3.2,4.0,5.0,6.3,7.9,10,13,16) % 09/26/06 repro: (0, .5, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10) % 9/30/04 growth: (0, .2,.32,.5,.8,1.3,2.0,3.2,5,8,13,20) % 7/17/06.

Genetic Toxicology

  • Salmonella  (325301)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Negative 
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