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Testing Status of Formic acid 10316-G


CASRN: 64-18-6

Formula: C-H2-O2

Synonyms/Common Names

  • Hydrogen Carboxylic acid

Known Uses

Fumigant, dyeing of textiles and paper, preparation of wire stripping compounds, manufacture of insecticides, animal feed additive, solvent for perfumes, natural component of foods, human tissues. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 2 weeks (Inhalation)  (C61905)  Completed 
    • Rats: F344/N; Mice: B6C3F1
  • 13 weeks (Inhalation)  (C61905)  Completed 
    • TOX-19 (NIH Number: 92-3342)
      Toxicity Studies of Formic Acid (CASRN 64-18-6) Administered by Inhalation to F344/N Rats and B6C3F1 Mice
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R & M 0, 8, 16, 32, 64, 128 PPM/10/GROUP.

Genetic Toxicology

  • Salmonella  (811661)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
    •  Negative