National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-10452-d

Testing Status of Sulfallate - 10452-D

 

CASRN: 95-06-7

Formula: C8-H14-Cl-N-S2

Synonyms/Common Names

  • Diethylcarbamodithioic Acid,2-Chloro-2-Propenyl Ester (9Ci)

Known Uses

Pre-emergence herbicide

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 14-Day (Dosed-Feed)  (C00453)  Completed 
    • Rats: Osborne Mendel; Mice: B6C3F1
  • 13-Week (Dosed-Feed)  (C00453)  Completed 
    • Rats: Osborne Mendel; Mice: B6C3F1
    • Dose: 0, 215, 4640 PPM/10 PER GROUP.

Long-Term Carcinogenicity

  • 2-Year (Dosed-Feed)  (C00453)  Report Complete 
    • TR-115 (NIH Number: 78-1370)  (Peer Review Approval 06/29/1978A )
      Bioassay of Sulfallate for Possible Carcinogenicity (CASRN 95-06-7)
    • Rats: Osborne Mendel; Mice: B6C3F1
    • Carcinogenesis Results
      • Male Rats Positive 
      • Female Rats Positive 
      • Male Mice Positive 
      • Female Mice Positive 
    • Dose: FR: 0, 250, 404 (AVG), MR: 0, 250, 410 (AVG), FM: 0, 908, 1815 (AVG), MM: 0, 949, 1897 (AVG) PPM/50 PER GROUP.

Genetic Toxicology

  • Salmonella  (747155)  Completed 
    • Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
    •  Positive 
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