Testing Status of Ferrocene 10495-W

 

CASRN: 102-54-5

Formula: C10-H10-Fe

Synonyms/Common Names

  • Bis(cyclopentadienyl)iron

Known Uses

Antiknock additive for gasoline. Catalyst. Ultraviolet absorber. Smoke inhibitor. Coating for missiles and satellites. Iron fertilizer, high temperature lubricant.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 2 weeks (Inhalation)  (C62066)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: 0, 2.5, 5, 10, 20, OR 40 MG/M3.
  • 13 weeks (Inhalation)  (C62066)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: 0, 3, 10, OR 30 MG/M3.

Special Studies

  • Absorption Disposition Metabolism Elimination (Inhalation; Intravenous)  (S0192)  Completed 
    • Male Rats: F344/N
    • Dose: INHAL: 20 NG/ML X 6 HR; IV BOLUS:1 MG/KG.

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (203142)  Completed 
    • Citation: Galloway, S., Bloom, A., Resnick, M., Margolin, B., Nakamura, F., Archer, P., and Zeiger, E. Development of a standard protocol for in vitro cytogenetic testing with CHO cells: Comparison of results for 22 compounds in two laboratories. Environ. Mutagen. Vol. 7 (1985) 1-52
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Negative 
  • In Vitro Cytogenetics (CA/SCE)  (674566)  Completed 
    • Citation: Galloway, S., Bloom, A., Resnick, M., Margolin, B., Nakamura, F., Archer, P., and Zeiger, E. Development of a standard protocol for in vitro cytogenetic testing with CHO cells: Comparison of results for 22 compounds in two laboratories. Environ. Mutagen. Vol. 7 (1985) 1-52
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Negative 
  • Drosophila  (455288)  Completed 
    • Citation: Zimmering, S., Mason, J.M., Valencia, R., and Woodruff, R.C. Chemical mutagenesis testing in Drosophila. II. Results of 20 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 87-100
    • Sex-Linked Recessive Lethal Positive 
    • Reciprocal Translocation Positive 
  • Salmonella  (077744)  Completed 
    •  Negative 
  • Salmonella  (373521)  Completed 
    • Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
    •  Equivocal 
  • Salmonella  (483456)  Completed 
    • Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
    •  Negative