National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-10511-x

Testing Status of p-Phenylenediamine - 10511-X

 

CASRN: 106-50-3

Formula: C6-H8-N2

Synonyms/Common Names

  • 1,4-Benzenediamine (9CI)

Known Uses

Chemical intermediate for dyes, aramid fibers, component of gasoline antioxidants, vulcanizing rubber; hair dyes

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Absorption Disposition Metabolism Elimination (Gavage; Intravenous)  (S0040)  Completed 
    • Citation: Ioannou YM, Matthews HB. p-Phenylenediamine dihydrochloride: comparative disposition in male and female rats and mice. J Toxicol Environ Health. 1985;16(2):299-313.Pubmed Abstract
    • Male and Female Rats: F344/N; Male and Female Mice: B6C3F1; Male and Female Rats: F344/N; Male and Female Mice: B6C3F1
    • Dose: PO: 6.5, 65 IV: 65 MG/KG.
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