Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of Diethylene glycol dimethyl ether 10536-H

 

CASRN: 111-96-6

Formula: C6-H14-O3

Synonyms/Common Names

  • Ethane, 1,1'-oxybis(2-methoxy-

Known Uses

Medium for grignard & similar reactions; solvent; anhydrous reaction medium for organometallic synthesis

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • Salmonella  (586320)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Negative 

Organ Systems Toxicity

  • 8 consecutive days (MTD PHASE), 7 to 14 GD (reproductive phase) Short-Term in vivo Repro. Tox. (Gavage)  (T0079A)  Completed 
    • Citation: Screening of Priority Chemicals for Potential Reproductive Hazard
    • Female Mice: Swiss
    • Dose: 3000 MG/KG BD WT.
  • 11 GD (PLUG=GD0) Conventional Teratology (Gavage)  (T0079E)  Completed 
    • Female Mice: Swiss
    • Dose: 537 MG/KG (4.0 MMOL/KG).
  • 6 to 15 GD Conventional Teratology (Gavage)  (TER85061)  Completed 
    • Citation: Teratologic Evaluation of Diethylene Glycol Dimethyl Ether Administered to CD-1 Mice on Gestational Days 6 through 15
    • Female Mice: Swiss
    • Mice Maternal Positive 
    • Mice Fetal Positive 
    • Dose: 0, 62.5, 125, 250, 500 MG/KG/DAY.
  • 6 to 19 GD Conventional Teratology (Gavage)  (TER86062)  Completed 
    • Citation: Teratologic Evaluation of Diethylene Glycol Dimethyl Ether Administered to New Zealand White Rabbits
    • Female Rabbit: New Zealand White
    • Rabbits Maternal Positive 
    • Rabbits Fetal Positive 
    • Dose: 0, 25, 50, 100, 175 MG/KG/DAY.