Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of Dibenzofuran 10580-Y

 

CASRN: 132-64-9

Formula: C12-H8-O

Synonyms/Common Names

  • (1,1'-Biphenyl)-2,2'-diyl oxide
  • 2,2'-Biphenylene oxide
  • Diphenylene oxide

Known Uses

Naturally occurring in coal tar. Component of heat-transfer oils. Used in polymer production and in dyeing and printing of textiles. Released into air from the incomplete combustion of coal & oil products. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Mechanisms (Gavage)  (S0464)  Completed 
    • Citation: Birnbaum LS, Harris MW, Crawford DD, Morrissey RE. Teratogenic effects of polychlorinated dibenzofurans in combination in C57BL/6N mice. Toxicol Appl Pharmacol. 1987 Nov;91(2):246-55.Pubmed Abstract
    • Mice: C57BL/6

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (578267)  Completed 
    • Citation: Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176
    • Sister Chromatid Exchange Weakly Positive 
    • Chromosome Aberrations Negative 
  • Salmonella  (618477)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Speck, W., and Zeiger, E. Mutagenicity testing of Agent Orange components and related chemicals Toxicology and Applied Pharmacology Vol. 75 (1984) 137-146
    •  Negative