National Toxicology Program

National Toxicology Program

Testing Status of Sodium dodecyl sulfate - 10604-G


CASRN: 151-21-3

Formula: C12-H26-O4-S.Na

Synonyms/Common Names

  • Sulfuric acid monododecyl ester sodium salt (9CI)

Known Uses

Surface-active agent. Emulsifying, foaming, wetting, dispersing agent for creams, lotions, medical preparations, foods, toothpaste, detergents, shampoos. In metal processing.

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • C. elegans  (W10604)  Completed 
    • C. elegans
    • Dose: Growth:0, 0.1, 0.16, 0.25, 0.40, 0.63, 1, 1.6, 2.5, 4, 6.3, 10mM.

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (908384)  Completed 
    • Sister Chromatid Exchange Negative 
    • Chromosome Aberrations Negative 
  • Mouse Lymphoma  (333852)  Completed 
    • Citation: McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
    • Mice
    •  Negative 
  • Salmonella  (251746)  Completed 
    •  Negative 
  • Salmonella  (988909)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Negative 
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.