National Toxicology Program

National Toxicology Program

Testing Status of Clonitralid - 10682-L


CASRN: 1420-04-8

Formula: C13-H8-Cl2-N2-O4.C2-H7-N-O

Synonyms/Common Names

  • 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide compd with 2-aminoethanol

Known Uses

Molluscicide and lamprey killer

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 14-Day (Dosed-Feed)  (C00431)  Completed 
    • Rats: Osborne Mendel; Mice: B6C3F1
  • 13-Week (Dosed-Feed)  (C00431)  Completed 
    • Rats: Osborne Mendel; Mice: B6C3F1
    • Dose: R: 0,2150,46400, M: 0,464,10000 PPM/5 PER GROUP.

Long-Term Carcinogenicity

  • 2-Year (Dosed-Feed)  (C00431)  Report Complete 
    • TR-091 (NIH Number: 78-1341)  (Peer Review Approval 06/29/1978A )
      Bioassay of Clonitralid for Possible Carcinogenicity (CASRN 1420-04-8)
    • Rats: Osborne Mendel; Mice: B6C3F1
    • Carcinogenesis Results
      • Male Rats Negative 
      • Female Rats Equivocal 
      • Male Mice Inadequate Study 
      • Female Mice Negative 
    • Dose: R: 0,14216,28433 (AVG), M: 0,274,549 (AVG) PPM/50 PER GROUP.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.