National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-10713-r

Testing Status of Agaritine - 10713-R

 

CASRN: 2757-90-6

Formula: C12-H17-N3-O4

Synonyms/Common Names

  • 5-(2-(4-Hydroxymethyl)phenyl)hydrazide)-L-Glutamic acid (9CI)

Known Uses

Anticancer drug, extracted from mushrooms.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 13 weeks (Dosed-Water)  (C08899)  Completed 
    • Mice: Swiss

Long-Term Carcinogenicity

  • 2 years (Dosed-Water)  (C08899)  Report Complete 
    •   (Peer Review Approval NA) Citation: B Toth, CR Raha, L Wallcave, D Nagel, Attempted Tumor Induction with Agaritine in Mice. Anticancer Res 1:255-258 (1981)
    • Mice: Swiss
    • Dose: 0,.03125,.0625,.125,.25 %.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.