National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-10735-p

Testing Status of C.I. Direct Red 39 - 10735-P

 

CASRN: 6358-29-8

Formula: C32-H28-N4-O8-S2.2Na

Synonyms/Common Names

  • 8-((4'-((4-ethoxyphenyl)azo)-3,3'-dimethyl(1,1'-biphenyl)-4-yl)azo)-7-hydroxy-, disodium salt

Known Uses

Dye for textiles, silk, wool, leather, paper

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Metabolism (Dosed-Feed; Gavage)  (S0022)  Completed 
    • Citation: Lynn RK, Donielson DW, Ilias AM, Kennish JM, Wong K, Matthews HB. Metabolism of bisazobiphenyl dyes derived from benzidine, 3,3'-dimethylbenzidine or 3,3'-dimethoxybenzidine to carcinogenic aromatic amines in the dog and rat. Toxicol Appl Pharmacol. 1980 Nov;56(2):248-58.Pubmed Abstract
    • Dog; Male Rats: Sprague Dawley

Genetic Toxicology

  • Salmonella  (281330)  Completed 
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
    •  Negative 
  • Salmonella Reduction  (418066)  Completed 
    • Citation: Reid, T., Morton K., and King, C. Mutagenicity of azo dyes following metabolism by different reductive/oxidative systems. Environ. Mutagen. Vol. 6 (1984) 705-717
    •  Positive 
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