Testing Status of Castor oil 10748-J

 

CASRN: 8001-79-4

Formula: N/F

Synonyms/Common Names

  • Phorbyol

Known Uses

Paint, cathartic, emollient, starting raw material for many basic industrial chemicals, machine lubricants, embalming fluids. In soap manufacture. For dyeing textiles. Plasticizer. In manufacture of fungicides. (Merck 1989)

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 13 weeks (Dosed-Feed)  (C55163B)  Report Complete 
    • TOX-12 (NIH Number: 92-3131)
      Toxicity Studies of Castor Oil (CASRN 8001-79-4) in F344/N Rats and B6C3F1 Mice (Dosed Feed Studies)
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R&M:0, .62, 1.25, 2.5, 5.0, 10.0%.

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (154774)  Completed 
    • Sister Chromatid Exchange Negative 
    • Chromosome Aberrations Negative 
  • Micronucleus  (A74921)  Completed 
    • Citation: Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194
    • Mice: B6C3F1
    • Male Negative 
    • Female Negative 
  • Salmonella  (743044)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
    •  Negative