Testing Status of Asbestos, chrysotile(IR) 10758-S

 

CASRN: 12001-29-5

Formula: H4-O4-Si.1/2H2-O.1/2Mg

Synonyms/Common Names

  • Asbestos, chrysotile

Known Uses

Asbestos, chrysotile: asbestos cement. Textiles. Insulation. Friction products. Fireproofing agent. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 13-Week (Dosed-Feed)  (C61234A)  Completed 
    • Rats: F344/N
  • 13-Week (Dosed-Feed)  (C61234B)  Completed 
    • Hamsters: Syrian Golden
  • 13-Week (Dosed-Feed)  (C61234E)  Completed 
    • Rats: F344/N

Long-Term Carcinogenicity

  • 2-Year (Dosed-Feed)  (C61234A)  Report Complete 
    • TR-295 (NIH Number: 86-2551)  (Peer Review Approval 07/27/1984A )
      Toxicology and Carcinogenesis Studies of Chrysotile Asbestos (CASRN 12001-29-5) in F344/N Rats (Feed Studies)
    • Rats: F344/N
    • Carcinogenesis Results
      • Male Rats Some Evidence 
      • Female Rats No Evidence 
    • Dose: 0, 1 %/250 PER GROUP.
  • 2-Year (Dosed-Feed)  (C61234B)  Report Complete 
    • TR-246 (NIH Number: 90-2502)  (Peer Review Approval 06/23/1981A )
      Lifetime Carcinogenesis Studies of Chrysotile Asbestos (CASRN 12001-29-5) in Syrian Golden Hamsters (Feed Studies)
    • Hamsters: Syrian Golden
    • Carcinogenesis Results
      • Male Hamsters Negative 
      • Female Hamsters Negative 
    • Dose: 0, 1 %/60 PER GROUP.
  • 2-Year (Dosed-Feed)  (C61234E)  Report Complete 
    • TR-295 (NIH Number: 86-2551)  (Peer Review Approval 07/27/1984A )
      Toxicology and Carcinogenesis Studies of Chrysotile Asbestos (CASRN 12001-29-5) in F344/N Rats (Feed Studies)
    • Rats: F344/N
    • Dose: 0, 1% /250 PER GROUP.