National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-10793-e

Testing Status of Tara gum - 10793-E

 

CASRN: 39300-88-4

Synonyms/Common Names

  • 2-Butanoic acid,2(Or 4)-isooctyl-4,6(Or 2,6)-dinitrophenyl ester (9CI)

Known Uses

In ice creams and cosmetics

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 14-Day (Dosed-Feed)  (C54364)  Completed 
    • Rats: F344/N; Mice: B6C3F1
  • 13-Week (Dosed-Feed)  (C54364)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: 0, 3100, 50000 PPM/10 PER GROUP.

Long-Term Carcinogenicity

  • 2-Year (Dosed-Feed)  (C54364)  Report Complete 
    • TR-224 (NIH Number: 81-1780)  (Peer Review Approval 02/18/1981A )
      Carcinogenesis Bioassay of Tara Gum (CASRN 39300-88-4) in F344 Rats and B6C3F1 Mice (Feed Study)
    • Rats: F344/N; Mice: B6C3F1
    • Carcinogenesis Results
      • Male Rats Negative 
      • Female Rats Negative 
      • Male Mice Negative 
      • Female Mice Negative 
    • Dose: 0, 25000, 50000 PPM/50 PER GROUP.

Genetic Toxicology

  • Salmonella  (487395)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
    •  Negative 
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