Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of Coconut oil acid diethanolamine condensate 10802-J

 

CASRN: 68603-42-9

Formula: Rc N(CH2CH2OH)2

Synonyms/Common Names

  • Amides, coco, N,N-bis(hydroxyethyl)
  • Coconut diethanolamide
  • Coconut oil acid diethanolamine (con 2/1)
  • Coconut oil acid/diethanolamine condensate

Known Uses

Foam stabilizer in shampoos and dishwashing liquids. Dyeing assistant in textile processing.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 13 weeks (Topical Application)  (C55312B)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R: 0, 25, 50, 100, 200, or 400 mg/kg; 20/sex/group M: 0, 50, 100, 200, 400, or 800 mg/kg; 10/sex/group.

Long-Term Carcinogenicity

  • 2 years (Topical Application)  (C55312B)  Completed 
    • TR-479 (NIH Number: 01-3969)  (Peer Review Approval 12/10/1997A )
      Toxicology and Carcinogenesis Studies of Coconut Oil Acid Diethanolamine Condensate (CASRN 68603-42-9) in F344/N Rats and B6C3F1 Mice (Dermal Studies)
    • Rats: F344/N; Mice: B6C3F1
    • Carcinogenesis Results
      • Male Rats No Evidence 
      • Female Rats Equivocal Evidence 
      • Male Mice Clear Evidence 
      • Female Mice Clear Evidence 
    • Dose: R: 0, 50, or 100 mg/kg M: 0, 100, or 200 mg/kg (50 sex/species/group).

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (898613)  Completed 
    • Sister Chromatid Exchange Negative 
    • Chromosome Aberrations Negative 
  • Mouse Lymphoma  (876640)  Completed 
    • Mice
    •  Negative 
  • Micronucleus  (A44271)  Completed 
    • Mice: B6C3F1
    • Male Positive 
    • Female Positive 
  • Salmonella  (104376)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
    •  Negative