National Toxicology Program

National Toxicology Program

Testing Status of Cadmium chloride - 10828-Y


CASRN: 10108-64-2

Formula: Cd-Cl2

Synonyms/Common Names

  • Dichlorocadmium

Known Uses

Galvanoplasty, lubricant ingredient, photography, dyeing & printing textiles; fungicide (Merck,1989)

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • C. elegans  (S0947)  Completed 
    • C. elegans

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (669323)  Completed 
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Positive 
  • Mouse Lymphoma  (402420)  Completed 
    • Citation: McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
    • Mice
    •  Positive 
  • Salmonella  (286441)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Negative 

Organ Systems Toxicity

  • 80 days Immunotoxicity (Gavage & Dosed-Water)  (IMM20001)  Completed 
    • Citation: Leffel, EK, Wolf C, Poklis, A and White Jr., KL. (2003) Drinking Water Exposure to Cadmium, an Environmental Contaminant, Results in the Exacerbation of Autoimmune Disease in the Murine Model. Toxicology 188: 233-250.
    • Female Rats: Brown-Norway
    • Dose: 0, 3, 30, OR 300 PPM.
  • 12 days Immunotoxicity (Gavage)  (IMM83003)  Completed 
    • Female Mice: B6C3F1
    • Dose: 0, 12, 20, OR 30 MG/KG.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.