National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-10843-v

Testing Status of Cytarabine - 10843-V

 

CASRN: 147-94-4

Related: CYTARABINE HYDROCHLORIDE 69-74-9

Formula: C9-H13-N3-O5

Synonyms/Common Names

  • 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone
  • Cytosine arabinoside

Known Uses

Antineoplastic, antiviral

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 14-Day (Intraperitoneal Injection)  (C04728)  Completed 
    • Rats: Sprague Dawley; Mice: Swiss
  • 13-Week (Intraperitoneal Injection)  (C04728)  Completed 
    • Rats: Sprague Dawley; Mice: Swiss

Long-Term Carcinogenicity

  • 2-Year (Intraperitoneal Injection)  (C04728)  Report Complete 
    •   (Peer Review Approval NA) Citation: EK Weisburger, Bioassay Program for Carcinogenic Hazards of Cancer Chemotherapeutic Agents. Cancer 40:1935-1949 (1977)
    • Rats: Sprague Dawley; Mice: Swiss
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