National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-10861-d

Testing Status of Myleran - 10861-D

 

CASRN: 55-98-1

Formula: C6-H14-O6-S2

Synonyms/Common Names

  • Busulfan
  • 1,4-Butanediol dimethanesulfonate (9CI)

Known Uses

Antineoplastic used in polycythemia and leukemia

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • Drosophila  (727535)  Completed 
    • Citation: Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 208-227
    • Sex-Linked Recessive Lethal Positive 
    • Reciprocal Translocation Positive 
  • Salmonella  (312927)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Positive 
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