National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-10870-g

Testing Status of Isoamyl nitrite - 10870-G

 

CASRN: 110-46-3

Formula: C5-H11-N-O2

Synonyms/Common Names

  • Nitrous acid, 3-methylbutyl ester

Known Uses

Cardiovascular dilator, used in perfumes, as vasodilator in treatment of poisonings, used in discos to stimulate dancing, as sexual stimulant (HSDB 1990).

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (556739)  Completed 
    • Citation: Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Positive 
  • Salmonella  (419564)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Positive 
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.