National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-10885-j

Testing Status of C.I. Direct Blue 25 - 10885-J

 

CASRN: 2150-54-1

Formula: C34-H26-N4-O16-S4.4Na

Synonyms/Common Names

  • 2,7-Naphthalenedisulfonic acid, 3,3'-((3,3'-dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(azo))bis(4,5-dihydroxy-, tetrasodium salt

Known Uses

Dye for leather, paper, silk, cotton, wool, nylon

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Metabolism (Dosed-Feed; Gavage)  (S0020)  Completed 
    • Citation: Lynn RK, Donielson DW, Ilias AM, Kennish JM, Wong K, Matthews HB. Metabolism of bisazobiphenyl dyes derived from benzidine, 3,3'-dimethylbenzidine or 3,3'-dimethoxybenzidine to carcinogenic aromatic amines in the dog and rat. Toxicol Appl Pharmacol. 1980 Nov;56(2):248-58.Pubmed Abstract
    • Female Dog; Male Rats: Sprague Dawley

Genetic Toxicology

  • Salmonella  (059158)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Negative 
  • Salmonella Reduction  (481183)  Completed 
    • Citation: Reid, T., Morton K., and King, C. Mutagenicity of azo dyes following metabolism by different reductive/oxidative systems. Environ. Mutagen. Vol. 6 (1984) 705-717
    •  Positive 
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