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Testing Status of 2,2',3,3',5,5'-Hexachlorobiphenyl 10909-S

 

CASRN: 35694-04-3

Formula: C12-H4-Cl6

Synonyms/Common Names

  • 2,2',3,3',5,5'-hexachloro-1,1'-biphenyl (9CI)

Known Uses

Dielectric fluids in liquid-cooled electric motors, transformers, capacitors; electromagnets, vacuum pumps, gas turbines, hydraulic fluids; heat-transfer systems; voltage regulators, fluorescent light ballasts, electronic equipment; plasticizers in synthetic resins, adhesives, surface coatings, sealants, printing and carbonless coping papers, pesticide extenders, inks, lubricants, & cutting oils.

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Absorption Disposition Metabolism Elimination (Intravenous)  (S0143)  Completed 
    • Citation: Matthews HB, Tuey DB. The effect of chlorine position on the distribution and excretion of four hexachlorobiphenyl isomers. Toxicol Appl Pharmacol. 1980 May;53(3):377-88.Pubmed Abstract
    • Male Rats: F344/N
  • Absorption Disposition Metabolism Elimination (Dosed-Feed)  (S0449)  Completed 
    • Citation: Colburn WA, Matthews HB. Pharmacokinetics in the interpretation of chronic toxicity tests: the last-in, first-out phenomenon. Toxicol Appl Pharmacol. 1979 May;48(3):387-95.Pubmed Abstract
    • Male Rats: Sprague Dawley
  • Absorption Disposition Metabolism Elimination (Intravenous)  (S0522)  Completed 
    • Citation: Matthews HB, Tuey DB. The effect of chlorine position on the distribution and excretion of four hexachlorobiphenyl isomers. Toxicol Appl Pharmacol. 1980 May;53(3):377-88.Pubmed Abstract
    • Rats: Sprague Dawley
  • Metabolism (Dosed-Feed)  (S0523)  Completed 
    • Citation: Kato S, McKinney JD, Matthews HB. Metabolism of symmetrical hexachlorobiphenyl isomers in the rat. Toxicol Appl Pharmacol. 1980 May;53(3):389-98.Pubmed Abstract
    • Male Rats: Sprague Dawley
  • Other (Dosed-Feed)  (S0774)  Completed 
    • Citation: Matthews HB, Surles JR, Carver JG, Anderson MW. Halogenated biphenyl transport by blood components. Fundam Appl Toxicol. 1984 Jun;4(3 Pt 1):420-8.Pubmed Abstract
    • Rats: Sprague Dawley

Organ Systems Toxicity

  • 6 to 15 GD Conventional Teratology (Gavage)  (T0144)  Completed 
    • Female Mice: Swiss
    • Dose: 0, 32, 64, 128 MG/KG/DAY.