National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-10937-h

Testing Status of Photodieldrin - 10937-H

 

CASRN: 13366-73-9

Formula: C12-H8-Cl6-O

Synonyms/Common Names

  • 2,4,6-Metheno-2H-cyclopenta(4,5)pentaleno(1,2-b)oxirene, 2a,3,3,4,5,5a-hexachlorodecahydro-, (1aR,1bR,2S,2aS,4R,5S,5aS,5bS,6S,6aS,7R)-

Known Uses

Photochemical conversion product of pesticide dieldrin

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 14-Day (Dosed-Feed)  (C00599)  Completed 
    • Rats: Osborne Mendel; Mice: B6C3F1
  • 13-Week (Dosed-Feed)  (C00599)  Completed 
    • Rats: Osborne Mendel; Mice: B6C3F1

Long-Term Carcinogenicity

  • 2-Year (Dosed-Feed)  (C00599)  Report Complete 
    • TR-017 (NIH Number: 77-817)  (Peer Review Approval 07/25/1977A )
      Bioassay of Photodieldrin for Possible Carcinogenicity (CASRN 13366-73-9)
    • Rats: Osborne Mendel; Mice: B6C3F1
    • Carcinogenesis Results
      • Male Rats Negative 
      • Female Rats Negative 
      • Male Mice Negative 
      • Female Mice Negative 

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (934568)  Completed 
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Negative 
  • Salmonella  (543366)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
    •  Positive 
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.