Testing Status of Carbaryl 10952-E

 

CASRN: 63-25-2

Formula: C12-H11-N-O2

Synonyms/Common Names

  • 1-Naphthalenol
  • 1-Naphthalenol, methylcarbamate

Known Uses

Contact insecticide. Parasiticide. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 4 days (Gavage)  (C10952)  Completed 
    • Liver Targeted Testing study of Toxcast Chemicals
    • Rats: Harlan Sprague-Dawley
    • Dose: Male rats: 0, 100 mg/kg/day.

Special Studies

  • C. elegans  (S0926)  Completed 
    • C. elegans
    • Dose: FEED: (0, .02, .032, .05, .08, .13, .25, .32, .5, .79, 1, 3, 2.0) 04/11/06; REPRO: (0, .01, .016, .025, .040, .063, .1, .16, .25, .40, .63. 1) 04/12/06 GROWTH: (0, .01, .016, .025, .04, .063, .1, .16, .25, .4, .63, 1 mM) 12/15/06.

Genetic Toxicology

  • 4 days Comet Assay (Gavage)  (G10952)  On Test 
    • Rats: Sprague Dawley

Toxicogenomics

  • 4 days Microarray Analysis (Gavage)  (T10952)  Completed 
    • Liver Targeted Testing study of Toxcast Chemicals
    • Rats: Harlan Sprague-Dawley
    • Dose: 100 mg/kg; 6 rats.