National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-10983-g

Testing Status of Cyclohexane - 10983-G

 

CASRN: 110-82-7

Formula: C6-H12

Synonyms/Common Names

  • Hexahydrobenzene

Known Uses

Solvent. Chemical intermediate. Obtained from petroleum (Merck 1989). Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Absorption Disposition Metabolism Elimination (Dosed-Feed; Gavage; Intravenous)  (S0038)  Completed 
    • Citation: Adsorption, Distribution, Metabolism and Excretion of Cyclohexane. Study dates: October 1931 - August 1983. Pharmacokinetics of Xenobiotics. June 1984.
    • Male Rats
    • Dose: IV: 10 PO: 100, 200, 1000, 2000 MG/KG.

Genetic Toxicology

  • Salmonella  (468809)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Negative 
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.