National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-10989-f

Testing Status of Dichloroacetonitrile - 10989-F

 

CASRN: 3018-12-0

Formula: C2-H-Cl2-N

Synonyms/Common Names

  • Dichloromethyl cyanide

Known Uses

Solvent in organic synthesis; byproduct from the disinfection of water

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (699204)  Completed 
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Weakly Positive 
  • Drosophila  (325373)  Completed 
    • Citation: Valencia, R., Mason, J.M., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: III. Results of 48 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 325-348
    • Sex-Linked Recessive Lethal Positive 
    • Reciprocal Translocation Negative 
  • Salmonella  (712321)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Positive 
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.