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Testing Status of 2-Ethylhexanol 11013-P


CASRN: 104-76-7

Formula: C8-H18-O

Synonyms/Common Names

  • 2-Ethyl-1-hexanol (9CI)
  • 2-Ethylhexyl alcohol

Known Uses

Plasticizer intermediate. Solvent. Wetting agent. Organic synthesis. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (463951)  Completed 
    • Sister Chromatid Exchange Negative 
    • Chromosome Aberrations Negative 
  • Salmonella  (134298)  Completed 
    • Citation: Zeiger, E., Haworth, S., Mortelmans, K., and Speck, W. Mutagenicity testing of Di(2-ethylhexyl)phthalate and related chemicals in Salmonella Environ. Mutagen. Vol. 7 (1985) 213-232
    •  Negative 

Organ Systems Toxicity

  • Short-Term in vivo Repro. Tox. (Gavage)  (T0055A)  Completed 
    • Citation: Screening of Priority Chemicals for Potential Reproductive Hazard
    • Female Mice: Swiss
    • Dose: 1525 MG/KG BODY WEIGHT.
  • 2 to 19 GD (sperm = 0 days) Conventional Teratology (Inhalation)  (T0162)  Completed 
    • Female Rats: Sprague Dawley
    • Dose: 800 MG/M3.
  • 0 to 17 GD Conventional Teratology (Dosed-Feed)  (TER90029)  Completed 
    • Citation: Final Report on the Developmental Toxicity of 2-Ethylhexanol in CD-1 Swiss Mice
    • Mice: Swiss
    • Mice Maternal Negative 
    • Mice Fetal Negative 
    • Dose: 0, .009, .030, .090%.