National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-11037

Testing Status of Isopropylated Phenol Phosphate - 11037

 

CASRN: 68937-41-7

Synonyms/Common Names

  • Durad 100
  • Flame Retardant 1
  • IPP
  • Isopropylated phenol phosphate (3:1)
  • Isopropylphenyl phosphate
  • Phenol isopropylated phosphate

Known Uses

Flame Retardants

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 5 days (Gavage)  (C10866B)  Completed 
    • Rats: Harlan Sprague-Dawley
    • Dose: 0, 0.169, 0.338, 0.675, 1.35, 2.70 mMol/kg; 5/species/dose.
  • 2 weeks (Dosed-Feed)  (C10866)  On Test 
    • Mice: B6C3F1/N
    • Dose: 0, 1875, 3750, 7500, 15000, or 30000 ppm; 5/sex.
  • 13 weeks (Dosed-Feed)  (C10866)  Assigned 
    • Mice: B6C3F1/N

Modified One-Generation

  • Dose Range Finding (Dosed-Feed)  (MOG10866)  On Test 
    • Rats: Harlan Sprague-Dawley
  • F0 Generation (Dosed-Feed) Selected (MOG10866B)  
    • Rats: Harlan Sprague-Dawley
  • Neurotoxicology Assessment (Dosed-Feed) Selected (MOG10866B)  
    • Rats: Harlan Sprague-Dawley

Special Studies

  • C. elegans  (W10866)  Completed 
    • C. elegans

Genetic Toxicology

  • Salmonella  (G10866)  Completed 
    •  Negative 

Toxicogenomics

  • Microarray Analysis (Gavage) Selected (T10866)  
    • Rats: Harlan Sprague-Dawley
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.