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Testing Status of Insertional Mutagenesis - Definitive Vector Study 11042

 

CASRN: INSERTMUT3

Secondary:

  • EFSSINVECTOR - EFS SIN Vector
  • LTRVECTOR - LTR Vector
  • NTPMOCKVEC - NTP MOCK Vector
  • PSINVECTOR - P(-) SIN Vector
  • SINVECTOR - SIN vector
  • UORFLTRVECTOR - uORF LTR Vector

Known Uses

Insertional mutagenesis studies using various vector exposures (LTR; uORF LTR, SIN, EFS LTR, and P(-) SIN vectors.

Long-Term Carcinogenicity

  • 14 months (Intravenous)  (C10844)  Data in Review 
    • Mice: C57BL/6
    • Dose: Female mice: 55/vector.