National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-11079-k

Testing Status of Benzo(f)-quinoline - 11079-K

 

CASRN: 85-02-9

Formula: C13-H9-N

Synonyms/Common Names

  • 5,6-Benzoquinoline

Known Uses

Reagent for cadmium, occurs in coal tars. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Absorption Disposition Metabolism Elimination (Gavage; Intravenous)  (S0042)  Completed 
    • Citation: Birnbaum LS, Johnson L. Disposition of benzo(f)quinoline in male rats. Drug Metab Dispos. 1985 Jan-Feb;13(1):18-24.Pubmed Abstract
    • Male Rats: F344/N
    • Dose: PO:1, 10, 100 MG/KG.

Genetic Toxicology

  • Salmonella  (403492)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Equivocal 
  • Salmonella  (934591)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Positive 
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