National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-11110-h

Testing Status of Dibenz(a,h)anthracene - 11110-H

 

CASRN: 53-70-3

Formula: C22-H14

Synonyms/Common Names

  • 1,2:5,6-Dibenzanthracene

Known Uses

In polyester & alkyd resins, inks, foods. Substitute for tartaric acid in baking powders. Antioxidant. Dye mordant. In manufacture of polyhydric alcohols. Occurs in coal tar, shellfish, mineral oils, foods. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • Salmonella  (381505)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
    •  Positive 

Organ Systems Toxicity

  • 28 days Immunotoxicity (Gavage)  (I11110)  Assigned 
    • Female Mice: B6C3F1
    • Dose: 0, 0.07, 0.2, 0.6, 2, 6, 17, and 50 mg/kg.
  • 28 days Immunotoxicity (Subcutaneous Injection)  (IMM20506)  Completed 
    • Immunosuppression Range Finding
    • Female Mice: B6C3F1
    • Dose: 0, 25, 79.3, 250, 793, or 2500 ug/kg.
  • 8 GD - PND 42 Immunotoxicity (Subcutaneous Injection)  (IMM20507)  Completed 
    • Developmental toxicity
    • Female Mice: B6C3F1
    • Dose: 0, 25, 79.3, 250, 793, or 2500 ug/kg.
  • 28 days Immunotoxicity (Subcutaneous Injection)  (IMM20607)  Completed 
    • Immunosuppression - Full Protocol
    • Female Mice: B6C3F1
    • Dose: 0, 250, 793, or 2500 ug/kg.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.