National Toxicology Program

National Toxicology Program

Testing Status of o-Phenanthroline - 11116-G


CASRN: 66-71-7

Formula: C12-H8-N2

Synonyms/Common Names

  • 1,10-Phenanthroline (9CI)

Known Uses

Detect trace amounts of iron, silver, nickel. In treatment of alimentary tract disorders. In high nitrogen enteral diets. For dietary control of metabolic disorders, fingernail treatment, diaper rash cream, cosmetics

Chemical Properties

Toxicity Effects (HSDB)

Nomination Background

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (864285)  Completed 
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Positive 
  • Salmonella  (897343)  Completed 
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
    •  Negative 
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.