National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-11122-y

Testing Status of Saccharin - 11122-Y

 

CASRN: 81-07-2

Formula: C7-H5-N-O3-S

Synonyms/Common Names

  • 1,1-Dioxide-1,2-benzisothiazol-3(2H)-one (9CI)

Known Uses

Non-caloric sweetener, formerly used as antiseptic & preservative, obtained from coal tar. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • Salmonella  (659833)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Negative 
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