National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-11136-x

Testing Status of Diethylene glycol monomethyl ether - 11136-X

 

CASRN: 111-77-3

Formula: C5-H12-O3

Synonyms/Common Names

  • 2-(2-Methoxyethoxy)ethanol

Known Uses

Textile dye pastes; in lacquer industrial for thinners & quick drying varnishes; solvent for wood stains, hydraulic brake fluid diluent, coupling agent for miscible organic aqueous systems

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • Salmonella  (776398)  Completed 
    •  Negative 

Organ Systems Toxicity

  • 8 consecutive days (MTD PHASE), 7 to 14 GD (reproductive phase) Short-Term in vivo Repro. Tox. (Gavage)  (T0077A)  Completed 
    • Citation: Determination of the Reproductive Effects in Mice of Nine Selected Chemicals
    • Female Mice: Swiss
    • Dose: 4000 MG/KG BD WT.
  • 7 to 16 GD (vaginal sperm = 1 GD) Conventional Teratology (Gavage)  (T0077B)  Completed 
    • Female Rats: Sprague Dawley
    • Dose: 720, 2165 mg/kg/day.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.