Testing Status of Triethylene glycol 11138-F

 

CASRN: 112-27-6

Formula: C6-H14-O4

Synonyms/Common Names

  • 2,2'-(1,2-Ethanediylbis(oxy))bis ethanol (9CI)

Known Uses

Gas conditioning agent. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (281692)  Completed 
    • Sister Chromatid Exchange Weakly Positive 
    • Chromosome Aberrations Negative 
  • Salmonella  (261099)  Completed 
    •  Positive 

Organ Systems Toxicity

  • continuous exposure, 120 day minimum Continuous Breeding (Legacy) (Dosed-Water)  (RACB83115)  Completed 
    • Citation: Final Report - Triethylene Glycol: Reproduction and Fertility Assessment in CD-1 Mice When Administered in the Drinking Water
    • Male and Female Mice: Swiss
    • Dose: 0, 1.0, 2.5, 5.0, 7.5, 10.0%; 0, .3, 1.5, 3.0%; N/A; 0, 3%.
  • 8 consecutive days (MTD PHASE), 7 to 14 GD (reproductive phase) Short-Term in vivo Repro. Tox. (Gavage)  (T0080A)  Completed 
    • Citation: Screening of Priority Chemicals for Reproductive Hazards
    • Female Mice: Swiss
    • Dose: 11270 MG(10ML UNDILUTED)/KG BD WT.