National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-11173-s

Testing Status of bis(Chloromethyl) ether - 11173-S

 

CASRN: 542-88-1

Formula: C2-H4-Cl2-O

Synonyms/Common Names

  • Oxybis(chloromethane)

Known Uses

Production of anion exchange resins, plastics, potential use in dental restorative materials. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Long-Term Carcinogenicity

  • lifetime (Inhalation)  (C06940)  Completed 
    • Rats: Sprague Dawley; Hamsters: Syrian Golden
    • Dose: R: 0, .1, 1, 2.1, 3.7, 6.9, 9.5 PPM H: 0, .1, .7, 1, 2.1, 5.6, 9.9 PPM /25-50 ANIMALS PER GROUP.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.