National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-11255-p

Testing Status of Aflatoxin-B1 - 11255-P

 

CASRN: 1162-65-8

Related: AFLATOXIN-B2 (CAS 7220-81-7) & AFLATOXINS (CAS 1402-68-2)

Formula: C17-H12-O6

Synonyms/Common Names

  • Cyclopenta(C)Furo(3',2':4,5)Furo(2,3-H)(1)Benzopyran-1,11-Dione-,2,3,6A,9A-Tetrahydro-4-Methoxy, (6Ar-Cis)- (9Ci)

Known Uses

Experimental purposes only. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Other (Dosed-Feed; Dosed-Water; Gavage)  (S0694)  Completed 
    • Citation: Robertson IG, Birnbaum LS. Age-related changes in mutagen activation by rat tissues. Chem Biol Interact. 1982 Jan;38(2):243-52.Pubmed Abstract
    • Female Rats: Long-Evans; Rats: Long-Evans
  • C. elegans  (W11255)  Completed 
    • C. elegans

Genetic Toxicology

  • Salmonella  (000003)  Completed 
    • Citation: Lawlor, T.E., Haworth, S.R., Zeiger, E., Park, D.L., and Lee, L.S. Mutagenic potential of ammonia-related aflatoxin reaction products in cottonseed meal J. Amer. Oil Chem. Soc. Vol. 62 (1985) 1136-1138
    •  Positive 
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