National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-11297-e

Testing Status of 1,3,5,7,9,11-Hexabromocyclododecane - 11297-E

 

CASRN: 25637-99-4

Formula: C12-H18-Br6

Synonyms/Common Names

  • Cyclododecane, hexabromo-
  • Flame Retardant 2
  • 1,3,5,7,9,11-HBCD

Known Uses

Flame retardant.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 5 days (Gavage)  (C11297)  On Test 
    • Rats: Hsd:Sprague Dawley SD
    • Dose: 0, 0.1, 1, 10, 100, or 1000 umol/kg; 6 males/group.

Genetic Toxicology

  • Salmonella  (045544)  Completed 
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
    •  Negative 

Toxicogenomics

  • 5 days Microarray Analysis (Gavage)  (T11297)  Assigned 
    • Rats: Hsd:Sprague Dawley SD
    • Dose: 0, 0.1, 1, 10, 100, or 1000 umol/kg; 6 males/group.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.