National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-11331-n

Testing Status of Asbestos, chrysotile(SR) - 11331-N

 

CASRN: 12001-29-5

Formula: H4-O4-Si.1/2H2-O.1/2Mg

Synonyms/Common Names

  • Asbestos, chrysotile

Known Uses

Asbestos, chrysotile: asbestos cement. Textiles. Insulation. Friction products. Fireproofing agent. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Nomination Background

Long-Term Carcinogenicity

  • 2-Year (Dosed-Feed)  (C61223A)  Report Complete 
    • TR-295 (NIH Number: 86-2551)  (Peer Review Approval 07/27/1984A )
      Toxicology and Carcinogenesis Studies of Chrysotile Asbestos (CASRN 12001-29-5) in F344/N Rats (Feed Studies)
    • Rats: F344/N
    • Carcinogenesis Results
      • Male Rats No Evidence 
      • Female Rats No Evidence 
  • 2-Year (Dosed-Feed)  (C61223B)  Report Complete 
    • TR-246 (NIH Number: 90-2502)  (Peer Review Approval 06/23/1981A )
      Lifetime Carcinogenesis Studies of Chrysotile Asbestos (CASRN 12001-29-5) in Syrian Golden Hamsters (Feed Studies)
    • Hamsters: Syrian Golden
    • Carcinogenesis Results
      • Male Hamsters Negative 
      • Female Hamsters Negative 
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.