National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-11337-l

Testing Status of Fumaric acid - 11337-L

 

CASRN: 110-17-8

Formula: C4-H4-O4

Synonyms/Common Names

  • Allomaleic acid
  • Boletic acid
  • 2-Butenedioic acid (E)- (9CI)
  • trans-Butenedioic Acid
  • trans-1,2-Ethylenedicarboxylic acid

Known Uses

Fortifier in paper size resins, substitute for tartaric acid, naturally occurring in plants. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • Salmonella  (450008)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
    •  Negative 
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