National Toxicology Program

Testing Status of Propionitrile - 11500-W

CASRN: 107-12-0

Formula: C3-H5-N

Synonyms/Common Names

• Propanenitrile (9CI)

Known Uses

Setting agent for resins. Raw material for some medicines. Intermediate. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

• In Vitro Cytogenetics (CA/SCE)  (522045)  Completed 
  • Citation: Loveday, K.S., Anderson, B.E., Resnick, M.A., and Zeiger, E. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro V: Results with 46 chemicals Environ. Molec. Mutagen. Vol. 16 (1990) 272-303
  • Sister Chromatid Exchange Negative 
  • Chromosome Aberrations Negative 
• Salmonella  (189070)  Completed 
  • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
  •  Negative 
• Salmonella  (582354)  Completed 
  • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
  •  Negative